General Information

  • ID:  hor004022
  • Uniprot ID:  NA
  • Protein name:  Locustapyrokinin-1
  • Gene name:  NA
  • Organism:  Locusta migratoria
  • Family:  Pyrokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  QDSGDEWPQQPFVPRL
  • Length:  16
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T1 Pyrrolidone carboxylic acid;T16 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Hindgut‐stimulating activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004022_AF2.pdbhor004022_ESM.pdb

Physical Information

Mass: 216678 Formula: C85H123N23O27
Absent amino acids: ACHIKMNTY Common amino acids: PQ
pI: 3.88 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 4
Hydrophobicity: -135 Boman Index: -4398
Half-Life: 0.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 42.5
Instability Index: 7953.13 Extinction Coefficient cystines: 5500
Absorbance 280nm: 366.67

Literature

  • PubMed ID:  11121115
  • Title:  Pyrokinin Neuropeptides in a Crustacean. Isolation and Identification in the White Shrimp Penaeus Vannamei